“At Green Bioactives we work with nature to create sustainable sources of plant biomolecules and extracts to supply the cosmetic, pharma, food and agricultural industries with premium bioactive ingredients”.
Plants are natures principal chemists, capable of producing a vast chemical cornucopia of natural biomolecules to protect themselves, for example, from infection, environmental pollutants and ultra-violet irradiation.
Green Bioactives has developed a sustainable, reliable, economical plant cell-based biomanufacturing platforms of plant biomolecules, utilising natural plant biochemistry
However, the yield of these biomolecules from plants is typically very low, the relevant plant species or their population might be limiting. Due to their complexity the chemical synthesis of these biomolecules is routinely not economically viable or sustainable.
Therefore, producing sufficient quantities of these natural biomolecules to meet rapidly growing public demand can be problematic.
These plant biomolecules are the core ingredients in many cosmetic, pharmaceutical, food and agricultural products.
Transforming the discovery, development and biomanufacturing of safe, sustainable, plant biomolecules.
To become the world’s leading supplier of safe, natural and sustainable plant biomolecules, while employing production processes that help protect and sustain our environment.
We believe our clients' success ensures our success. We strive to achieve these outcomes by creating and nurturing positive customer (and employee) relationships, with a respect for well-being, together with a strong focus on innovation, dynamism and adaptability.
Green Bioactives Ltd was established through the Innovation to Commercialisation of University Research (ICURe) programme funded by Innovate UK. In 2018 Green Bioactives Ltd was awarded a place on the ICURe programme to explore the global plant natural products market and identified an urgent requirement for a robust and sustainable source of plant bioactive molecules across different industrial sectors.
Subsequently, Green Bioactives was awarded significant Innovate UK funding to accelerate the development of our plant cell biomanufacturing platform and supply plant bioactive ingredients in a sustainable way.
The company opened its research lab at the Roslin Innovation Centre (RIC) in March 2020. Since then Green Bioactives has been successful in securing further funding and developing new technologies to fine-tune the production of high-value molecules in cultured plant cells.
Green Bioactives, a Biotech CDMO with aspirations to develop its own product lines
Green Bioactives is an innovative start-up from the University of Edinburgh which utilizes a next-generation plant cell-based biomanufacturing platform to produce biomolecules and cell extracts for the cosmetic, pharmaceutical, food and agricultural markets.
The RIC is embedded within the Easter Bush campus of the University of Edinburgh. It is surrounded by the Pentlands Science Park, Edinburgh Technopole, and the Midlothian Biocampus which collectively is one of Europe’s largest biotechnology clusters.
Green Bioactives provides CDMO services to companies that require a reliable supply of high-value plant biomolecules
2018 ICURe market research
2019 Company formation
ICURe Follow on funding awarded
Innovation Cup runner up
2020 Relocation to the Roslin Innovation Centre
BBSRC grant awarded
Patent application filed
IBioIC grant awarded
Collaboration agreement signed
2021 Strengthening of our plant cell biomanufacturing platform
IBioIC grant awarded
GBL team expanded
Participation in Bioeconomy cluster Pitch event
2022 Expansion phase
Our plant cell biomanufacturing platform combines a number of enabling technologies, know-how and IP which allow us to control de complete process to increase the yield of a target plant molecule. Our workflow ranges from the generation of high-performance cell lines to the exploitation of plants' biochemical pathways and genetic screening to attain significant yield improvements of the products made by these cells. These technologies are applicable for use in a wide variety of plant-based systems.
Green Bioactives uniquely blends plant cell isolation and culture, with cell line selection and scale-up, delivering high-performance production lines for commercialisation at scale.
Plant Cell Line Generation
Green Bioactives is able to apply extensive experience together with the latest scientific advances to generate plant cell lines from target tissues or organs for the commercial scale synthesis of a given plant natural product.
Process Development and Scale-Up
Process development and scale-up expertise guides the optimisation of bioprocess conditions. This enables Green Bioactives to create robust, competitive and scalable processes to sustainably biomanufacture plant natural products.
Bioengineering and Genomics
Green Bioactives uniquely combines metabolic engineering, genomics and natural selection, creating proprietary systems for the bio-manufacture of high-quality plant natural products. Our multidisciplinary team blends experience and cutting-edge know-how, delivering all aspects of the development pipeline from project conception through to commercial-scale manufacture, with a focus on yield enhancement.
Screen Development and Cell Line Selection
We design tailored product assays, combining classical techniques with cutting-edge metabolic engineering to precisely monitor target biomolecule biosynthesis. These provide a simple, reliable and practical means to identify both high-performing GM and non-GM plant cell production lines.
Our expertise and technical capabilities allow us to develop products containing plant natural products according to our customers' specifications.